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革兰阴性杆菌感染现状及应对措施
引用本文:何新华,李春盛. 革兰阴性杆菌感染现状及应对措施[J]. 中国新药与临床杂志, 2006, 25(5): 375-379
作者姓名:何新华  李春盛
作者单位:首都医科大学附属北京朝阳医院,急诊科,北京,100020
摘    要:细菌感染已经成为临床不可忽视的问题。在感染菌谱中,革兰阴性杆菌感染具有明显加剧趋势,且耐药现象日趋严重,严重影响了药物的疗效和疾病的预后。本文就革兰阴性杆菌感染现状、耐药状况、耐药机制以及应对措施进行综述,为临床合理选择抗生素提供依据。

关 键 词:革兰阴性菌  感染  抗感染药  耐药性
文章编号:1007-7669(2006)05-0375-05
收稿时间:2006-02-21
修稿时间:2006-02-212006-04-03

Current status and control of gram-negative bacillus infection
HE Xin-hua,LI Chun-sheng. Current status and control of gram-negative bacillus infection[J]. Chinese Journal of New Drugs and Clinical Remedies, 2006, 25(5): 375-379
Authors:HE Xin-hua  LI Chun-sheng
Affiliation:Department of Emergency, Beijing Chaoyang Hospital Affiliated to Capital University of Medical Sciences, BEIJING 100020, China
Abstract:Bacterial infections are so seriously conducted making us always on alert and not be negligible. After antibiotics have been extensively used, nearly all infections are now under controlled, but a new problem concerned about the antibiotics-resistance of bacteria has emerged clinically. Among the wide spectrum of infections, gram negative bacillus infection becomes more seriously aggravated with increasing drug resistances attenuating the action of drugs, and affecting the prognosis. A comprehensive review of literatures for understanding the current of gram negative bacillus infection, drug resistance together with its mechanism is presented in this article with the hope of providing proper evidence for antibiotics selection clinically.
Keywords:gram-negative bacteria   infection    anti-infective agents    drug resistance
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