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Surface-conditioned dental implants: an animal study on bone formation |
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| Authors: | Bernd Stadlinger Anna Theresa Lode Uwe Eckelt Ursula Range Falko Schlottig Thomas Hefti Ronald Mai |
| Affiliation: | Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Technology Dresden, Dresden, Germany;;Institute for Medical Informatics and Biometry, Faculty of Medicine, University of Technology Dresden, Dresden, Germany;;Thommen Medical AG, Waldenburg, Switzerland |
| Abstract: | Aim: The aim of this study was to determine whether bone formation around surface-conditioned implants is enhanced compared with non-surface-conditioned sandblasted acid-etched titanium implants. Materials and Methods: One hundred and forty-four implants were placed in the mandible of 18 minipigs. Before placement, implants were either surface conditioned in a solution containing hydroxide ions (conSF) or assigned to controls. Animals were euthanized after 2, 4 and 8 weeks of submerged healing, the 8-week group receiving polyfluorochrome labelling at week 2, 4, 6 and 8. One jaw quadrant per animal was selected for histological and histomorphometrical evaluation of mineralized bone–implant contact (mBIC), osteoid–implant contact (OIC) and bone volume (BV) analysis. Results: Polyfluorochrome labelling showed no general differences in bone dynamics. mBIC showed the most pronounced differences after 2 weeks, reaching 65.5% for conSF compared with 48.1% for controls, p =0.270. Differences levelled out after 4 weeks (67.4% control, 65.7% conSF) and 8 weeks (64.0% control, 70.2% conSF). OIC levels were initially comparable, showing a slower decline for conSF after 4 weeks. BV was higher for conSF at all times. No significant differences could be found. Conclusion: A tendency towards increased mBIC was shown for surface-conditioned implants after short-term healing. |
| Keywords: | conditioning dental implant histomorphometry osseointegration |