眼睑皮肤松垂程度与年龄的关系——三级转诊中心的前瞻性研究

目的：调查眼睑皮肤松垂的位置和程度及是否伴随假性上睑下垂与年龄的关系。方法：选取113例眼睑皮肤松垂患者纳入本研究,记录患者的年龄,性别及体质指数。于第一眼位检测睑裂高度和睑缘至瞳孔反射点距离( MRD)。皮肤松垂的程度分为1级：皮肤松垂未及睑缘(至少距睑缘1 mm)；2级：皮肤松垂达睑缘水平；3级：皮肤松垂越过睑缘前。结果：患者平均年龄为52.7±8.6(32~74)a。男36例(31.9％),女77例(68.1％)。平均体质指数为30.3±4.7(21.5~36.6)kg/m2,平均睑裂高度为10.7±1.6(7~15)mm,平均MRD为3.8±1.2(1~5) mm。30例(26.5％)患者的皮肤松垂未及睑缘(1级),38例(33.6％)患者位于睑缘水平线(2级),而45例(39.8％)患者越过睑缘前(3级)。50例(44.2％)患者由于皮肤松垂引起假性上睑下垂。皮肤松垂程度在年龄方面的差异显著。皮肤松垂1级和2级患者的平均年龄(50.3±6.6,50.5±9.5岁)明显低于3级患者年龄(56.0±8.2岁)。假性上睑下垂患者(56.3±8.3岁)的平均年龄明显高于非假性上睑下垂患者(49.8±7.8岁)。对于皮肤松垂严重程度和假性上睑下垂,患者体质指数无显著差别。结论：皮肤松垂严重程度和假性上睑下垂的发生率随年龄的增长而有所增加。

Relationship between dermatochalasis and more prominent with aging: a prospective study in a tertiary referral center

AIM: To investigate the localization and severity of dermatochalasis and accompanying pseudoptosis with age.

METHODS:One hundred and thirteen subjects with dermatochalasis were included in the study. Age, gender and body mass index(BMI)of the subjects were recorded. Palpebral fissure height(PFH)and marginal reflex distance(MRD)were measured in the primary position. The severity of dermatochalasis was assesed as Stage 1: behind eyelid margin(minimum 1 mm); Stage 2: inline with eyelid margin; Stage 3: before eyelid margin.

RESULTS: Mean age of the subjects were 52.7±8.6(range 32 to 74)y. Thirty-six cases(31.9%)were male and 77(68.1%)were female. The mean BMI was 30.3±4.7(range 21.5 to 36.6)kg/m², mean PFH was 10.7±1.6(range 7 to 15)mm, mean MRD was 3.8±1.2(range 1 to 5)mm. In 30(26.5%)of the subjects dermatochalasis was localized behind eyelid margin, in 38(33.6%)it was inline with eyelid margin and in 45(39.8%)it was before eyelid margin. There was pseudoptosis due to dermatochalasis in 50(44.2%)of the subjects. Age was significantly different in terms of dermatochalasis severity. Mean ages of subjects with dermatochalasis localization behind or inline with eyelid margin(50.3±6.6, 50.5±9.5y), were significantly lower than subjects with dermatochalasis localization before eyelid corner(56.0±8.2y). Mean age of subjects with pseudoptosis were significantly higher(56.3±8.3y), than subjects without it(49.8±7.8y). There was no BMI difference between the subjects in terms of dermatochalasis severity and presence of pseudoptosis.

CONCLUSION:Dermatochalasis localization, severity and frequency of pseudoptosis increase with age.