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妊娠期高血压疾病血钙水平与血液流变学指标的相关性
引用本文:吴文英,徐春琳,王翠芹,李海霞.妊娠期高血压疾病血钙水平与血液流变学指标的相关性[J].中国妇幼保健,2008,23(25):3519-3521.
作者姓名:吴文英  徐春琳  王翠芹  李海霞
作者单位:1. 河北医科大学第二医院妇产科北,石家庄,050000
2. 河北省唐山市丰润区人民医院妇产科
摘    要:目的:分析妊娠期高血压疾病患者血钙与血液流变学指标的变化,探讨血钙与血液粘度之间的相关性。方法:采用病例对照研究方法,选取90例妊娠期高血压疾病患者为妊娠期高血压疾病组,其中包括妊娠期高血压22例、子痫前期68例(子痫前期轻度38例、子痫前期重度30例);46例正常晚孕妇女为正常晚孕组;38例非孕健康妇女为对照组。比较3组血钙及血液粘度水平差异,同时分析妊娠期高血压疾病血钙及血液粘度之间的相关性。结果:妊娠期高血压疾病患者与正常晚孕妇女相比,血钙水平显著降低,血液粘度明显升高,差异有显著性(P<0.01)。妊娠期高血压疾病患者血钙水平与全血高、中、低切粘度及血浆粘度均呈显著负相关关系,Spearman等级相关系数分别为-0.698、-0.723、-0.776和-0.824,P<0.01。结论:妊娠期高血压疾病血钙及血液粘度存在着明显的异常变化,且血钙及血液粘度之间存在着负相关性。

关 键 词:妊娠期高血压疾病  血液粘度  血钙

Investigation of correlation between the levels of blood calcium and index of hemorheology in patients with pregnancy induced hypertension
Abstract:Objective:To analyze the changes of blood calcium and index of hemorheology in patients with pregnancy induced hypertension(PIH) and to investigate their correlation.Methods:A case-control study was used for determining the levels of blood calcium and blood viscosity in 174 cases.Correlation analysis of them was maded.Results:The blood calcium level was decreased significantly and blood viscosity levels was increased significantly in PIH patients.There was significant difference among the three groups,there was negative correlation between the whole-blood viscosity at low,medium and high shear and blood calcium in PIH patients,their correlation coefficients were -0.698,-0.723,-0.77 and -0.824,respectively.Conclusion:There are great changes between the levels of blood calcium and blood viscosity in PIH,presenting negative correlation.
Keywords:Pregnancy induced hypertension  Blood viscosity  Blood calcium
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