Calcium channel blocker nilvadipine,but not diltiazem,inhibits ocular inflammation in endotoxin-induced uveitis |
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Authors: | Susumu Ishida Takashi Koto Norihiro Nagai Yuichi Oike |
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Affiliation: | Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan. ishidasu@med.hokudai.ac.jp |
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Abstract: | Purpose Calcium channel blockers (CCBs), widely used for hypertensive patients, have recently been shown to inhibit atherosclerosis by their antioxidative action. The aim of the present study was to examine whether the CCBs nilvadipine and diltiazem reduce ocular inflammation in endotoxin-induced uveitis (EIU). |
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