| 急性肩袖损伤早期修复过程中不同强度应力刺激的生物力学反应 |
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| 引用本文： | 王鹏程,靳安民,付国建,李森,张飞,许勇. 急性肩袖损伤早期修复过程中不同强度应力刺激的生物力学反应[J]. 中国组织工程研究与临床康复, 2010, 14(11). DOI: 10.3969/j.issn.1673-8225.2010.11.018 |
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| 作者姓名： | 王鹏程 靳安民 付国建 李森 张飞 许勇 |
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| 作者单位： | 南方医科大学附属珠江医院骨科中心,广东省广州市,510282 |
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| 摘 要： | 背景:持续应力刺激已经证明可以促进肩袖损伤的修复,实验尝试在肩袖损伤修复的全过程中进一步量化应力刺激的强度,寻求到达更好的治疗效果.目的:观察不同强度应力刺激在急性肩袖损伤后修复过程中的生物力学表现.方法:取成年雄性新西兰大白兔36只,随机分为大强度实验组、小强度实验组和对照组,每组12只.将冈上肌腱于大结节止点处横断后原位缝合(隧道法),建立兔冈上肌腱损伤模型.术后石膏绷带制动1周后,采用关节持续被动器(CPM)进行功能锻炼,大强度训练组活动范围为-60°～60°,小强度训练组活动范围为-15°～15°,术后第2周,隔天训练,10 min/次;第3周开始每天训练,10 min/次;第4周15 min/次.对照组自由活动.于术后2,3,4,周每组各取4只动物取材,分别比较冈上肌腱-骨界面的刚度和最大抗拉强度的变化.结果与结论:各时间观察,小强度训练组的最大抗拉强度和刚度均明显强对照组和大强度训练组(P＜0.05),大强度训练组最大抗拉强度和刚度最弱,各组断裂点均存肌腱缝合处.结构表明,小强度应力刺激在急性肩袖损伤早期修复中效果较佳,而大强度应力刺激在急性肩袖损伤早期修复中起损伤作用.
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| 关 键 词： | 应力刺激 强度 肩袖损伤 牛物力学分析 兔 肌肉肌腱组织工程 |
Biomechanical response to stress stimulation with different intensities during early repair period of acute rotator cuff injury |
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| Wang Peng-cheng,Jin An-min,Fu Guo-jian,Li Sen,Zhang Fei,Xu Yong. Biomechanical response to stress stimulation with different intensities during early repair period of acute rotator cuff injury[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2010, 14(11). DOI: 10.3969/j.issn.1673-8225.2010.11.018 |
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| Authors: | Wang Peng-cheng Jin An-min Fu Guo-jian Li Sen Zhang Fei Xu Yong |
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| Affiliation: | Wang Peng-cheng,Jin An-min,Fu Guo-jian,Li Sen,Zhang Fei,Xu YongOrthopedics Center of Zhujiang Hospital,Southern Medical University,Guangzhou 510280,Guangdong Province,China |
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| Abstract: | BACKGROUND: Continuing stress stimulation has been confirmed to promote repair of rotator cuff injury. This experiment attempts to further quantify the intensity of stress stimulation in order to reach a better therapeutic effect in the entire process of rotator cuff injury repair. OBJECTIVE: To explore the biomechanical performance of stress stimulation with different intensities on repair of acute rotator cuff injury. METHODS: Sixteen male New Zealand rabbits were randomly divided into high intensity, low... |
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