| 铜绿假单胞菌联合滑石粉治疗恶性胸腔积液临床观察 |
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| 引用本文： | 黄崇标,崔焱,辛亮,杨彦卓,齐大亮. 铜绿假单胞菌联合滑石粉治疗恶性胸腔积液临床观察[J]. 天津医药, 2011, 39(9): 797-799. DOI: 10.3969/j.issn.0253-9896.2011.09.008 |
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| 作者姓名： | 黄崇标 崔焱 辛亮 杨彦卓 齐大亮 |
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| 作者单位： | 天津医科大学附属肿瘤医院高级病房, 天津市肿瘤防治重点实验室,300060 |
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| 摘 要： | 目的:观察铜绿假单胞菌制剂联合滑石粉治疗恶性胸腔积液的疗效。方法:74例恶性胸腔积液患者经皮穿刺置管彻底引流胸腔积液,随机分成3组,治疗组28例,为铜绿假单胞菌联合滑石粉治疗组;对照组A共26例,为滑石粉对照组;对照组B共20例,为铜绿假单胞菌对照组。将滑石粉或铜绿假单胞菌制剂溶于生理盐水,经胸腔置管于胸腔内注射,每周1次,连用1～3周。1个月复查,比较3组的总有效率及发热、胸痛等不良反应发生率。结果:治疗组总有效率高于2个对照组(χ2分别为6.273和4.255,均P<0.05)。3组均未发生严重并发症,治疗组及对照组B患者接受干预后白细胞数较对照组A高(P<0.01);对照组B发生胸痛比例较治疗组及对照组A低(P<0.05);治疗组和对照组中度以上发热比例差异无统计学意义(P>0.05)。结论:铜绿假单胞菌联合滑石粉治疗恶性胸腔积液是一种安全有效的治疗方法。
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| 关 键 词： | 假单胞菌,铜绿 胸腔积液,恶性 滑石粉 胸膜固定术 治疗 |
Clinical Observation of PA-MSHA Combined with Talcum Powder in the Treatment of Malignant Pleural Effusion |
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| HUANG Chongbiao,CUI Yan,XIN Liang,YANG Yanzhuo,QI Daliang. Clinical Observation of PA-MSHA Combined with Talcum Powder in the Treatment of Malignant Pleural Effusion[J]. Tianjin Medical Journal, 2011, 39(9): 797-799. DOI: 10.3969/j.issn.0253-9896.2011.09.008 |
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| Authors: | HUANG Chongbiao CUI Yan XIN Liang YANG Yanzhuo QI Daliang |
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| Affiliation: | HUANG Chongbiao,CUI Yan,XIN Liang,YANG Yanzhuo,QI DaliangCancer Institute and Hospital of Tianjin Medical University,Tianjin Key Laboratory of Cancer Treatment and Prevention,Tianjin 300060,China |
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| Abstract: | Objective:To prospectively study the clinical efficacy of combined administration of pseudomonas aeruginosa-mannose sensitive hemagglutinin(PA-MSHA) and talcum powder in the treatment of malignant pleural effusion.Methods:Seventy-four patients suffered from malignant pleural effusion were randomly divided into three groups,observation group(n=28),talcum powder group(A group,n=26) and PA-MSHA group(B group,n=20).Patients in the observation group were given combined treatment of PA-MSHA and talcum powder.All ... |
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| Keywords: | pseudomonas aeruginosa pleural effusion malignant PULVIS TALCI pleurodesis therapy |
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