336例原发性中晚期肝癌介入治疗中碘油用量及临床分析

目的：探讨中晚期肝癌介入治疗中导管位置与碘油量的关系以及碘油用量对临床疗效、副作用的影响。方法：回顾采用肝固有动脉给药的病例86例及高度选择性栓塞治疗的肝癌250例，并比较二者的疗效、副作用与碘用量的关系。结果：本组病例肝癌大小3－15cm，86例为肝固有动脉给药治疗1－3次者，碘油用量5－10ml/次，肿瘤明显缩小20例（23％），2年生存5例（6％）。高度选择性栓塞治疗1－3次的250例，碘油用量15－40ml／次，肿瘤明显缩小163例（65％），2年生存78例（31％）。结论：肝癌超选择性栓塞的碘油用量与疗效成正比，副反应随碘油用量轻微增高；固有动脉栓塞疗效较差、副作用大。

Amount of lipiodol and clinical analysis of 336 cases of large liver cancer in interventional therapy

Objective :To evaluate the relationship between place of catheter and amount of lipiodol and its in- fluence upon clinical effects and negative effects. Methods :86 cases of transcatheter proper hepatic arterial em- bolization and 250 cases of super selective segmental transarterial embolization(STAE) were analyzed respective- ly and curative effects and negative effects of the two and the relationship with amount of lipiodol were com- pared. Results: Liver neoplastic size of all cases were 3 - 15cm. For 86 cases of proper hepatoarterial emboliza- tion, the amount of lipiodol was 5 - 10ml. Obvious tumor shrinking occurred in 20 cases(23% ) , the 2-year sur- vival in 5 cases (6%).For 250 cases of STAE,the amount of lipiodol was 15 - 40ml. Obvious tumor shrinking occurred in 163cases (65%) ,the 2 - year survival occurred in 78 cases(31%). Conclusion :For STAE,amount of lipiodol is in direct proportion to curative effects and negative effects increase slightly as the amount of lipiodol increases. For transcatheter proper hepatic arterial embolization,curative effects were poor,negative effects were obvious.