栾树的化学成分

目的：分离鉴定栾树(Koelreuteria paniculata Laxm)叶的化学成分。方法：95%工业EtOH浸提,硅胶柱色谱分离,IR,MS,UV,1HNMR,¹³CNMR等方法确定结构。结果：分得14个化合物,分别为对-二没食子酰乙酯(ethyl-p-digallate)(1),间二没食子酰乙酯(ethyl-m-digallate)(2),对-二没食子酸(p-digalloyl acid)(3),间-二没食子酸(m-digalloyl acid)(4),2″-没食子酰基槲皮素苷(quercitrin-2″-gallate)(5),没食子酸(galloyl acid)(6),没食子酸乙酯(ethyl galloyl acid)(7),鞣花酸(ellagic acid)(8),槲皮苷(quercitrin)(9),金丝桃苷(hyperin)(10),山奈酚-3-O-鼠李糖苷(kaempferol-3-O-rhamnoside)(11),2″-没食子酰金丝桃苷(hyperin-2″-gallate)(12),β-谷甾醇(β-sitosterol)(13),β-谷甾醇-3-O-葡糖苷(β-sitosterol 3-O-gluceroside)(14)。结论：对-二没食子酰乙酯(ethyl-p-digallate)(1),间二没食子酰乙酯(ethyl-m-digallate)(2),对-二没食子酸(p-digalloyl acid)(3)为新化合物,化合物4,5,8～12和14系首次从该植物中分得。并首次系统归属其波谱信号。

CHEMICAL CONSTITUENTS FROM THE LEAVES OF KOELREUTERIA PANICHLATA LAXM

AIM: Isolation and structural elucidation of the constituents from leaves of the Chinese medicinal plant Koelreuteria paniculata Laxm. METHODS: The leaves were extracted with 95% EtOH percolation and the crude extracts were purified by using silica gel chromatography. IR, UV, MS, 1H and ¹³CNMR spectra were employed for structural identification. RESULTS: Three new compounds named ethyl-p-digallate (1), ethyl-m-digallate (2), p-digalloyl acid (3), together with eleven known compounds m-digalloyl acid (4), quercitrin-2″-gallate (5), galloyl acid (6), ethyl galloyl acid (7), ellagic acid (8), quercitrin (9), hyperin (10), kaempferol-3-O-rhamnoside (11), hyperin-2″-gallate (12),β-sitosterol (13) and β-sitosterol 3-O-glucoside (14) were isolated. CONCLUSION: Ethyl-p-digallate (1), ethyl-m-digallate (2) and p-digalloyl acid (3) were new compounds, and 4, 5, 8～12 and 14 were known compounds unreported previously from this plant.