| 植物内生菌HCCB00167产物的发酵、分离和结构鉴定 |
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| 引用本文： | 解翠华,阮丽君,夏焕章,陈代杰,葛梅. 植物内生菌HCCB00167产物的发酵、分离和结构鉴定[J]. 沈阳药科大学学报, 2007, 24(4): 245-248 |
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| 作者姓名： | 解翠华 阮丽君 夏焕章 陈代杰 葛梅 |
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| 作者单位： | 1. 沈阳药科大学,制药工程学院,辽宁,沈阳,110016
2. 上海来益生物药物研究开发中心,上海,201203 |
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| 摘 要： | 目的对植物内生菌HCCB00167发酵产物酯溶性部分的化合物进行分离和结构鉴定。方法采用乙酸乙酯萃取、硅胶柱色谱制备分离纯化;通过质谱和核磁共振等谱学数据进行化学结构鉴定。结果从HCCB00167菌株发酵液中分离并鉴定了3个化合物,分别为麦角甾醇(1)、过氧化麦角甾醇(2)和4-丁基-吡啶-2-羧酸(3)。结论其中4-丁基-吡啶-2-羧酸为首次从陆生真菌中得到。
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| 关 键 词： | 麦角甾醇 过氧化麦角甾醇 4-丁基-吡啶-2-羧酸 结构鉴定 |
| 文章编号： | 1006-2858(2007)04-0245-04 |
| 修稿时间： | 2006-06-09 |
Fermentation products of endophyte HCCB00167 |
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| XIE Cui-hua,RUAN Li-jun,XIA Huan-zhang,CHEN Dai-jie,GE Mei. Fermentation products of endophyte HCCB00167[J]. Journal of Shenyang Pharmaceutical University, 2007, 24(4): 245-248 |
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| Authors: | XIE Cui-hua RUAN Li-jun XIA Huan-zhang CHEN Dai-jie GE Mei |
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| Abstract: | Objective To investigate the chemical constituents from endophyte HCCB000167.Methods The chemical constituents were isolated by using the solvent extraction,silica gel chromatography.The structures were identified on the basis of mass spectrum,1H-NMR 13C-NMRand planar NMR.Results Three compounds were isolated from HCCB000167 culture broth,which were identified as ergosterol(1),ergosterol peroxide(2),4-butyl-pyridine2-carboxylic acid(3).Conclusions Compound 3 is found from terraneous eumycete for the first time. |
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| Keywords: | ergosterol ergosterol peroxide 4-butyl-pyridine-2-carboxylic acid structure identification |
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