| PET脑视功能区自动提取的研究 |
| |
| 引用本文： | 张剑戈,郭万华,李培勇,王成,江旭峰,潘家普,朱承谟. PET脑视功能区自动提取的研究[J]. 上海交通大学学报(医学版), 2003, 23(1): 24-27 |
| |
| 作者姓名： | 张剑戈 郭万华 李培勇 王成 江旭峰 潘家普 朱承谟 |
| |
| 作者单位： | 上海第二医科大学生物医学工程教研室，上海第二医科大学生物医学工程教研室，上海第二医科大学生物医学工程教研室，瑞金医院核医学科，瑞金医院核医学科，瑞金医院核医学科，瑞金医院核医学科 上海 200025，上海 200025，上海 200025 |
| |
| 摘 要： | 目的建立自动提取脑部功能区的方法。 方法通过非线性的空间变换将PET图像经过图像配准和图像形变两个步骤,归一化到Talairach坐标系,根据图谱中脑功能区的坐标,在3D图像中提取相应的功能区;为验证功能区提取的有效性,对志愿者带眼罩和不带眼罩各14例,加光刺激,提取视区并染色,计算经小脑归一化后的平均密度值。 结果两组视区平均密度值显著性差异(P<0.001);视区位置符合解剖学定义。 结论自动提取功能区的方法是有效的。
|
| 关 键 词： | 视区 配准 空间归一化 PET 断层显像技术 |
| 文章编号： | 0258-5898(2003)01-0024-04 |
| 修稿时间： | 2002-04-10 |
The Study of Automatic Functional Area of Brain Extraction in PET Images |
| |
| ZHANG Jian-ge,GUO Wan-hua,LI Pei-yong,et al. The Study of Automatic Functional Area of Brain Extraction in PET Images[J]. Journal of Shanghai Jiaotong University:Medical Science, 2003, 23(1): 24-27 |
| |
| Authors: | ZHANG Jian-ge GUO Wan-hua LI Pei-yong et al |
| |
| Abstract: | Objective To establish a method which can extract functional areas of the brain automatically. Methods 18F - FDG PET images were spatially normalized to Talairach Atlas space through two steps, image registration and image deformation. The functional areas were extracted from 3D PET images based on the coordinate extracted from Atlas; 14 volunteers with an eyepatch and 14 volunteers without an eyepatch were stimulated by light. Brodmann 17 area was extracted and rendered, the grey value of the area was normalized by the cerebellum, then the grey mean of the whole area was measured. Results The grey mean between two groups had significant difference (P <0.001). The position of Brodmann 17 area corresponded to the anatomical definition. Conclusion The automatic functional area extracted method proved officacious. |
| |
| Keywords: | Brodmann 17 area registration spatial normalization PET |
| 本文献已被 CNKI 等数据库收录！ |
|
