THE EFFECT OF RENAL DENERVATION ON ACTH-INDUCED HYPERTENSION IN SHEEP |
| |
| Authors: | Judith A. Whitworth D. A. Denton W. F. Graham T. J. Humphery B. A. Scoggins J. P. Coghlan |
| |
| Affiliation: | Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Victoria, Australia;*Department of Nephrology, The Royal Melbourne Hospital, Victoria, Australia |
| |
| Abstract: | 1. The effect of renal denervation on ACTH-induced hypertension in sheep has been examined. 2. Both intact and renally denervated sheep showed similar rises in blood pressure following ACTH treatment. 3. Following renal denervation, the initial urinary sodium retention and ACTH-withdrawal natriuresis typical of ACTH administration in intact sheep were absent, and the fall in blood pressure was delayed. |
| |
| Keywords: | ACTH hypertension renal denervation sheep sodium |
|
|
