| 急性心肌梗死患者血浆脂联素和超敏C-反应蛋白的临床分析 |
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| 引用本文： | 马香稳,王宪,李建.急性心肌梗死患者血浆脂联素和超敏C-反应蛋白的临床分析[J].中国临床实用医学,2010,4(3):31-33. |
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| 作者姓名： | 马香稳 王宪 李建 |
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| 作者单位： | 山东省潍坊市妇幼保健院内分泌科,261011 |
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| 摘 要： | 目的探讨急性心肌梗死（AMI）患者血浆脂联素（APN）和超敏C-反应蛋白（hs．CRP）的变化及其临床意义。方法选择AMI患者50例，人院后均行超声心动图检查评价室壁运动和心功能，并设对照组（30例）进行比较。采用ILISA法测定APN，免疫散射比浊法检测hs．CRP水平。结果AMI患者APN水平显著低于正常心功能对照组（P〈0．01），hs—CRP水平显著高于正常心功能对照组（P〈0．01）。AMI患者APN、hs—CRP水平与左心室射血分数（LVEF）呈负相关（r=-0．549，P〈0．01）。结论血浆APN、hs-CRP水平与预后显著相关，对AMI的辅助诊断、疗效观察及预后判断具有重要价值。
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| 关 键 词： | 急性心肌梗死 脂联素 超敏C-反应蛋白 |
Clinical analysis of plasma adiponectin and hs-CRP in patients with acute myocardial infarction |
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| MA Xiang-wen,WANG Xian,LI Jian.Clinical analysis of plasma adiponectin and hs-CRP in patients with acute myocardial infarction[J].China Clinical Practical Medicine,2010,4(3):31-33. |
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| Authors: | MA Xiang-wen WANG Xian LI Jian |
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| Institution: | .( Department of Endocrinology, Women and Children Hospital, Weifang , Shangdong Province 261011, China) |
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| Abstract: | Objective To explore the variation and significance of plasma adiponectin(APN) and high sensitivety C-reactive protein( hs-CRP) in patients with acute myocardial infarction(AMI). Methods The cases were divided into two groups:AMI group (including 50 AMI patients)and control group (including 30 normal individuals). Plasma concentration of APN was measured by ILISA and hs-CRP was measured by immue nephelonretry. Results The concentration of APN in patients with AMI were significantly lower than those in the control group ( P ＜ 0.01 ), hs-CRP were significantly higher than those in the control group ( P ＜ 0.01 ). The concentration of APN and hs-CRP in AMI patients had a parallel rationship with LVEDD (r = 0.549, P ＜ 0,01 ). Conclusion Plasma APN and hsCRP levels are of great value to the diagnosis, treatment and prognosis of AMI. |
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| Keywords: | Acute myocardial infarction Adiponectin High sensitivity C-reactive protein |
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