| 灵芝多糖引起的小鼠脾细胞核DNA，RNA含量及核质比的变化 |
| |
| 引用本文： | 肖军军,雷林生,赵翔,林志彬.灵芝多糖引起的小鼠脾细胞核DNA，RNA含量及核质比的变化[J].中国药理学与毒理学杂志,1994(3). |
| |
| 作者姓名： | 肖军军 雷林生 赵翔 林志彬 |
| |
| 作者单位： | 北京医科大学细胞生物学教研室，广州第一军医大学药理学教研室 |
| |
| 摘 要： | 灵芝多糖可引起体外培养的小鼠脾细胞核ＤＮＡ，ＲＮＡ含量显著增加，细胞内超微结构改变，细胞质和细胞核的平均截面积明显增加，核质比呈下降趋势，提示灵芝多糖诱导脾细胞ＤＮＡ和蛋白质合成的同时，促进细胞增殖。
|
| 关 键 词： | 多糖类，灵芝，脱氧核糖核酸，核糖核酸，脾，淋巴细胞 |
Changes of nuclear DNA,KNA contents and ratio of nucleus to cytoplasm of murine splenocytes induced by Ganoderma lucidum polysaccharides |
| |
| XIAO Jun-Jun,LEI Lin-Sheng,ZHAO Xiang,LIN Zhi-Bin.Changes of nuclear DNA,KNA contents and ratio of nucleus to cytoplasm of murine splenocytes induced by Ganoderma lucidum polysaccharides[J].Chinese Journal of Pharmacology and Toxicology,1994(3). |
| |
| Authors: | XIAO Jun-Jun LEI Lin-Sheng ZHAO Xiang LIN Zhi-Bin |
| |
| Abstract: | The changcs of nuclear DNA,RNAcontents and ratio of nucleus to cytoplasm of murine spleen cells mediated by Ganoderma lucidum polysaccharides(GLP)were studied using acytofluorophotometer and electron microscope.It wasfound that GLP 50-200 mg·L-1 not only increasedthe contents of nuclear DNA and RNA but also re-markably changed the cell ultrastructure and meancross section areas of nucleus and cytoplasm and re-duced the ratio of nucleus to cytoplasm.These resultsindicated that GLP could increase the synthesis of nu-clear acid and protein and promote cell proliferation inmurine splenocvtes. |
| |
| Keywords: | polysaccharide Ganodermalucidum DNA RNA spleen lymphocytes |
| 本文献已被 CNKI 等数据库收录！ |
