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终末期肾衰竭透析患者血脂改变的临床观察
引用本文:沈明静,阳晓,叶任高. 终末期肾衰竭透析患者血脂改变的临床观察[J]. 中国中西医结合肾病杂志, 2003, 4(10): 585-586
作者姓名:沈明静  阳晓  叶任高
作者单位:1. 广东省深圳市龙岗中心医院肾内科,深圳,518116
2. 中山大学附属第一医院肾内科,广州,510080
摘    要:目的:观察连续性非卧床腹膜透析(CAPD)和维持性血液透析(MHD)患血脂水平改变。方法:对634例CAPD和45例MHD患血脂水平进行测定,并以40例正常人作对照。结果:CAPD和MHD患血TG和apoB显增高,血HDL—c、apoAl、apoAl/apoB均显低于正常,以上指标在血、腹透组之间部分存在显性差异。CAPD组在发生腹膜炎后血LDL—c、apoB较未发生之前显增高。结论:CAPD和MHD患脂质紊乱相当常见,以前更为突出。当发生腹膜炎时脂质代谢紊乱更加严重。

关 键 词:终末期肾衰竭 透析疗法 血脂 维持性血液透析 腹膜透析
修稿时间:2003-03-17

The Clinical Observation of Lipids Change of Dialysis-Patients with End-Stage Renal Failure
SHEN Mingjing,YANG Xiao,YE Rengao. The Clinical Observation of Lipids Change of Dialysis-Patients with End-Stage Renal Failure[J]. Chinese Journal of Integrated Traditional and Western Nephrology, 2003, 4(10): 585-586
Authors:SHEN Mingjing  YANG Xiao  YE Rengao
Abstract:Objective:To investigate the blood lipid profile of CAPD and MHD patients..Methods:To determine the lipid levels of CAPD( n =63) and MHD( n =45), and to compare the results with the control group ( n =40). Results:Compared with control group, the blood TG and apoB increased while HDL-c, apoA1, apoA1/apoB decreased significantly in CAPD and MHD patients. There was significant difference between the 2 groups concerning the above lipid parameters. Blood LDL-c, apoB increased significantly after peritonitis.Conclusion:Hyperlipidemia is quite common in dialysis patients, which seems to be more obvious in CAPD patients. It was more severe when complicated with peritonitis.
Keywords:Peritoneal dialysis Hemodialysis Lipid metabolism
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