BHT-920 and LY-171555 (quinpirole) have similar affinities for striatal D-2 dopamine receptors, and similar affinities for striatal D-1 dopamine receptors |
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Authors: | S Ferré T Guix J Sallés L Cuffí A Badia M Casas |
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Affiliation: | Laboratori de Neuropsicofarmacologia, Programa Sant Pau-CITRAN, Hospital de la Santa Creu i de Sant Pau, Barcelona, Spain. |
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Abstract: | The affinity of LY-171555 (quinpirole) and BHT-920 for both states of rat striatal dopamine D-1 and D-2 receptors was determined. Although these drugs have different pharmacological effects in experimental animals, we found that they had similar affinities for both D-1 and D-2 receptors. |
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