中国北方结肠憩室的患病率及其增长趋势

目的探讨中国北方结肠憩室发病趋势的变化。方法选择2011年1月-2015年12月在天津医科大学宝坻临床学院及天津医科大学总医院的消化内镜中心进行肠镜检查的26 463例患者,分析患者年龄、年患病率及年代增长情况。结果共确诊为结肠憩室患者951例(3.59%),其中72.87%为右半结肠憩室,11.88%为左半结肠憩室,15.25%为两侧结肠憩室。憩室的患病率从2011年的2.78%(112/4 028)增长至2015年的4.98%(309/6 208)(P 0.01,趋势分析)。右半结肠憩室好发年龄60岁,左半结肠憩室好发年龄≥60岁。男性和年龄增长均是发生结肠憩室的独立危险因素。结论随着人口老龄化、生活方式的西方化及城市工业化,中国北方的憩室患病率正在逐步增加。

Prevalence and growth trend of colonic diverticulosis in northern China

To determine the trends in diverticulosis over the past owing to data scarcity from Northern China. Methods 26 463 colonoscopies performed from January 2011 to December 2015 were reviewed respectively. The trends in diverticulosis were analyzed in terms of age growth and year increase. Results 951 colonic diverticulosis were identified. A preponderance of right-sided diverticulosis were demonstrated, accounting for 72.87% of included subjects. The proportion of colonic diverticulosis increased significantly (P < 0.01 for trend) from 2.78% (112/4 028) in 2011 to 4.98% (309/6 208) in 2015. Multivariate analysis showed older age and male gender were independent risk factor for the incidence of diverticulosis. Conclusion Colonic diverticulosis has been increasing in Northern China, where a rapid aging and urbanization is ongoing.