Economic Burden of NSAID-induced Gastropathy in Sweden |
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| Authors: | B. Jönsson U. Haglund |
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| Affiliation: | 1. Division of Internal Medicine, Department of Medicine and Care, University Hospital, Link?ping, Sweden;2. Division of Cell Biology, Department of Biomedicine and Surgery, Faculty of Health Sciences, University Hospital, Link?ping, Sweden;3. Department of Pathology Research, Ryhov Hospital, J?nk?ping, Sweden;4. Division of Surgery, Department of Biomedicine and Surgery, Faculty of Health Sciences, University Hospital, Link?ping, Sweden |
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| Abstract: | Background: Gastrointestinal side effects carry a significant cost related to the use of NSAID medications. Methods: The economic burden of NSAID-induced gastric side effects is estimated using the cost-of-illness methodology. Costs are calculated using both a prevalence (top-down) approach and an incidence (bottom-up) approach. Results: Using the top-down approach, the total cost in 1998 of NSAIDinduced ulcers was MSEK 329-586, direct costs accounting for 76%-83%. The bottom-up approach gives an estimate of MSEK 320, of which MSEK 290 was direct cost. About one-quarter of total costs for ulcer disease can be attributed to the use of NSAIDs. Conclusions: Gastrointestinal side effects carry a significant cost from the use of NSAIDs, costs that are as important as the price of NSAIDs. This should be considered when choice of drug and prophylaxis is being made. |
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| Keywords: | Direct Costs Economic Burden Gastropathy Indirect Costs Nsaids Sweden |
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