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Hypothermia and Infection I. Influence of Hypothermia on Antibody Formation in Mice in the Secondary Response to Typhoid-H-Antigen
Authors:T Lindner  G Tunevall
Institution:1. The Central Bacteriological Laboratory of Stockholm City, Nortull's Hospital, Stockholm, Sweden;2. The Wenner-Gren Research Laboratory, Nortull's Hospital, Stockholm, Sweden
Abstract:Öckerman, P. A. Lysosomal Acid Hydrolases in the Liver in Gargoylism. Deficiency of 4-methylumbelliferyl-β-galactosidase. Scand. J. clin. Lab. Invest. 22, 142-146, 1968.

The activites of six lysosomal acid hydrolases were measured in liver biopsy specimens from six patients with gargoylism and in post-mortem tissue from two patients. A marked diminution was noted for the activity of 4-methylumbelliferyl-β-glactosidase in all patients with gargoylism. The deficiency of β-galactosidase did not seem to be due to the presence of an inhibitor in the liver.

The activities of β-glucuronidase, β-acetylglucosaminidase, acid phosphatase and α-fucosidase were significantly increased in some of the patients. The activity of α-mannosidase was not significantly different from the values in the controls.
Keywords:β-acetylglucosaminidase  acid hydrolases  acid phosphatase  α-fucosidase  β-galactosidase  gargoylism  β-glucuronidase  liver  lysosomes  α-mannosidase
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