Hypothermia and Infection I. Influence of Hypothermia on Antibody Formation in Mice in the Secondary Response to Typhoid-H-Antigen |
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Authors: | T Lindner G Tunevall |
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Institution: | 1. The Central Bacteriological Laboratory of Stockholm City, Nortull's Hospital, Stockholm, Sweden;2. The Wenner-Gren Research Laboratory, Nortull's Hospital, Stockholm, Sweden |
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Abstract: | Öckerman, P. A. Lysosomal Acid Hydrolases in the Liver in Gargoylism. Deficiency of 4-methylumbelliferyl-β-galactosidase. Scand. J. clin. Lab. Invest. 22, 142-146, 1968.The activites of six lysosomal acid hydrolases were measured in liver biopsy specimens from six patients with gargoylism and in post-mortem tissue from two patients. A marked diminution was noted for the activity of 4-methylumbelliferyl-β-glactosidase in all patients with gargoylism. The deficiency of β-galactosidase did not seem to be due to the presence of an inhibitor in the liver.The activities of β-glucuronidase, β-acetylglucosaminidase, acid phosphatase and α-fucosidase were significantly increased in some of the patients. The activity of α-mannosidase was not significantly different from the values in the controls. |
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Keywords: | β-acetylglucosaminidase acid hydrolases acid phosphatase α-fucosidase β-galactosidase gargoylism β-glucuronidase liver lysosomes α-mannosidase |
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