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18F-Fluorodeoxyglucose positron emission tomography in Whipple's disease |
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| Authors: | Marc F. J. André Isabelle Delèvaux Florent Cachin Florence Fenollar Didier Raoult Jean Maublant |
| Affiliation: | 1. Service de Médecine Interne, H?pital Gabriel Montpied, Clermont-Ferrand, Francemandre@chu-clermontferrand.fr;3. Service de Médecine Interne, H?pital Gabriel Montpied, Clermont-Ferrand, France;4. Service de Médecine Nucléaire, Centre Jean Perrin, Clermont-Ferrand, France;5. Unité des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine, Université de la Méditerranée, Marseille, France |
| Abstract: | AbstractWe report four patients with pancreatic fistulas that failed to respond to conservative treatment. The fistulas were closed by endoscopic injection of N-butyl-2-cyanoacrylate (Histoacryl) diluted with an oily contrast agent (Lipiodol). A literature review revealed 32 similar cases in which endoscopic treatment with fibrin sealants (n = 11) or cyanoacrylate (n = 21) was used to close the fistulas. Based on our own experience and the literature review, we conclude that endoscopic sealing of pancreatic fistulas can be performed safely and effectively by experienced endoscopists in a tertiary centre. The procedure seems useful in the management of complicated pancreatic fistulas which do not respond to conservative treatment and may obviate the need for surgery. |
| Keywords: | Endoscopic retrograde cholangiopancreatography interventional endoscopy pancreas |