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Primary autoimmune haemolytic anaemia and coeliac disease
Authors:M. Gabrielli  M. Candelli  F. Franceschi  F. Cremonini  E. C. Nista  L. Santarelli
Affiliation:1. Depts. of Internal Medicine and Angiology and Internal Medicine and Gastroenterology, Catholic University the Sacred Heart, Rome, Italy;2. Dept. of Experimental Medicine, La Sapienza, Rome, Italy
Abstract:Background: Irritable bowel syndrome is a common cause of abdominal pain and discomfort and may be related to disordered gastrointestinal motility. Our aim was to assess the effects of long-term treatment with a prokinetic agent, cisapride, on postprandial jejunal motility and symptoms in the irritable bowel syndrome (IBS). Methods: Thirty-eight patients with IBS (constipation-predominant, n = 17; diarrhoea-predominant, n = 21) underwent 24-h ambulatory jejunal manometry before and after 12 week's treatment {cisapride, 5mg three times daily (n = 19) or placebo (n = 19)}. Results
Keywords:Coeliac disease  HLA-DQ  immunoperoxidase staining  jejunal biopsy specimens  lamina propria lymphocytes  monoclonal antisera
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