Prophylactic antibiotic treatment in acute necrotizing pancreatitis: East wind blows no good |
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Authors: | Maxim S Petrov Romana D Pylypchuk |
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Institution: | 1. Department of Surgery, Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russiamax.petrov@gmail.com;3. Department of Epidemiology, Maastricht University, Maastricht, The Netherlands |
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Abstract: | The thermolability of amylase was measured in saliva, pancreatic juice, urine, adult and neonatal sera. The mean percentage thermolability from these fluids was 100%, 99%, 87%, 44% and 23% respectively. In patients with acute pancreatitis and mumps the amylase was 84% and 83% thermolabile during the acute phase. On resolution of the pancreatitis this dropped towards normal. Patients with a pancreatic pseudocyst showed a high mean percentage thermolability (82%). These results could suggest that a component of amylase in human serum is not of pancreatic or salivary origin. In addition, this simple technique may be helpful in the diagnosis of pancreatic pseudocyst. |
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Keywords: | Amylase enzyme thermolability iso-enzymes mumps pancreatic pseudocyst pancreatitis |
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