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原发性肝癌肝移植后肿瘤复发的化疗栓塞治疗
引用本文:周斌,李征然,钱结胜,朱康顺,姜在波,关守海,黄明声,庞鹏飞,单鸿.原发性肝癌肝移植后肿瘤复发的化疗栓塞治疗[J].介入放射学杂志,2009,18(3).
作者姓名:周斌  李征然  钱结胜  朱康顺  姜在波  关守海  黄明声  庞鹏飞  单鸿
作者单位:广州中山大学附属第三医院介入科,510630
基金项目:广东省自然学科基金团队研究项目 
摘    要:目的 评价介入化疗栓塞在HCC肝移植后肿瘤复发治疗中的作用.方法 12例原发性HCC肝移植后肿瘤复发、且失去外科治疗机会的患者接受1次或多次TACE治疗(平均每例2.28次).通过治疗后的影像学资料判定治疗反应,并用Kaplan-Meier生存曲线计算患者生存率.结果 12例中7例(58.3%)肿瘤体积缩小≥30%.然而,在随访期间有11例(91.3%)出现了肝内或肝外新发病灶.移植后1、2、3和4年生存率分别为83.3%、57.1%、47.6%和17.9%;复发后6、12和24个月生存率分别为66.7%,50%和31.3%.结论 对于原发性HCC肝移植后肿瘤复发且失去外科切除机会的患者,介入化疗栓塞在一定程度上可以控制肿瘤生长.

关 键 词:化疗栓塞  肝细胞癌  复发  肝移植

Chemoembolization for recurrent hepatocellular carcinoma after liver transplantation
ZHOU Bin,LIZheng-ran,QIAN Jie-sheng,ZHU Kang-shun,JIANG Zai-bo,CUAN Shou-hai,HUANG Ming-sheng,PANG Peng-fei,SHAN Hong.Chemoembolization for recurrent hepatocellular carcinoma after liver transplantation[J].Journal of Interventional Radiology,2009,18(3).
Authors:ZHOU Bin  LIZheng-ran  QIAN Jie-sheng  ZHU Kang-shun  JIANG Zai-bo  CUAN Shou-hai  HUANG Ming-sheng  PANG Peng-fei  SHAN Hong
Institution:ZHOU Bin,LIZheng-ran,QIAN Jie-sheng,ZHU Kang-shun,JIANG Zai-bo,GUAN Shou-hai,HUANG Ming-sheng,PANG Peng-fei,SHAN Hong. Department of Interventional Radiology,the Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,China
Abstract:Objective To evaluate the interventional chemoembolization in treating unresectable recurrent hepatocellular carcinoma (HCC) after liver transplantation. Methods Twelve patients with unresectable recurrent HCC underwent one or more cycles (mean 2.25 cycles) of transarterial chemoemboliza-tion (TACE) after liver transplantation. The results were evaluated by follow-up CT scans and were classified into four grades. The survival rate was calculated by using Kaplan-Meier survival curve. Results No severe compli...
Keywords:chemoembolization  hepatocellular carcinoma  recurrence  liver transplantation  
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