| 支气管动脉灌注顺铂的血药浓度监测 |
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| 引用本文： | 李智岗,孟祥文.支气管动脉灌注顺铂的血药浓度监测[J].介入放射学杂志,1994,3(1):30-32. |
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| 作者姓名： | 李智岗 孟祥文 |
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| 作者单位： | 河北医学院附属第四医院放射科，山西医学院附属第二医院放射科 050011 |
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| 摘 要： | 笔者通过对15例不能手术肺癌患者支气管动脉灌注顺铂的血药浓度监测,对靶器官及周围组织的血药浓度——时间曲线进行了分析。结果表明,在支气管动脉灌注过程中,靶器官的血药浓度明显高于周围组织的血药浓度,且靶器官的血药浓度大大超过了顺铂的有效抗癌浓度,为支气管动脉灌注治疗肺癌提供了可靠的理论依据,并对灌注过程中应注意的事项进行了分析,对于指导临床治疗具有重要意义.
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| 关 键 词： | 支气管动脉 灌注法 顺铂 血药浓度 肺肿瘤 |
Monitoring of Cisplatin Concentration in Blood during Bronchial Artery Infusion |
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| Li Zhi-gang.Monitoring of Cisplatin Concentration in Blood during Bronchial Artery Infusion[J].Journal of Interventional Radiology,1994,3(1):30-32. |
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| Authors: | Li Zhi-gang |
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| Institution: | Li Zhi-gang Department of Radiology,Fourth Affiliated Hospital,Hebei Medical College,Shijiazhang |
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| Abstract: | Monitoring of cisplatin concentration in blood was done in 15 cases with inoperable lung cancer during bronchial artery infusion.The curve of time drug concentration in blood in target organ and peripheral tissue were analysed.Results showed that the drug concentration in target was evident higher than that in peripheral tissue,and the drug concentration in target organ was much higher than the effective drug concentration,therefore. a reliable theory was given for treatment of lung cancer by bronchial artery infusion. |
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| Keywords: | Bronchial artery Infusion Location cisplatin drug concentration |
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