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益肾活血胶囊抗病毒性心肌炎的实验研究
引用本文:胡善宏,顾法伟,贾青,王朝霞,张维东. 益肾活血胶囊抗病毒性心肌炎的实验研究[J]. 齐鲁药事, 2004, 23(4): 52-53
作者姓名:胡善宏  顾法伟  贾青  王朝霞  张维东
作者单位:1. 日照市卫生防疫站,日照,276800
2. 山东省医学科学院基础研究所,济南,250062
摘    要:目的 探讨益肾活血胶囊对病毒性心肌炎的治疗作用。方法 选用BALB/C小鼠 6 0只,随机分为正常对照组、模型组、益肾活血胶囊组、阳性药物组,每组分别给药后,测定LDH和AST含量,并进行组织病理学检测,各区测定值采用t检验进行组间比较。结果 益肾活血组小鼠LDH、AST水平较模型组明显降低,(p <0 0 0 1);组织病理学检测发现,心脏组织病理改变程度较模型组明显减轻。结论 益肾活血胶囊对于病毒性心肌炎模型小鼠有一定的治疗作用。

关 键 词:益肾活血胶囊  小鼠  乳酸脱氢酶  天冬氨酸氨基转氨酶  病理组织学
文章编号:1672-7738(2004)04-0052-02

The experiment of treating viral myocorditis by the Yishenhuoxue Capsules
Hu Shan-hong,Gu Fa-wei,Jia Qing,Wang Zhao-xia,Zhang Wei-dong. The experiment of treating viral myocorditis by the Yishenhuoxue Capsules[J]. qilu pharmaceutical affairs, 2004, 23(4): 52-53
Authors:Hu Shan-hong  Gu Fa-wei  Jia Qing  Wang Zhao-xia  Zhang Wei-dong
Affiliation:Hu Shan-hong,Gu Fa-wei,Jia Qing1,Wang Zhao-xia1,Zhang Wei-dong1
Abstract:Objective To disccuss the effect of the Yishenhuoxue capsule treating viral myocarditis.Methods 60 BALB/C mouse were divided into 4 groups:nomal comparison group,model group,Yishenhuoxue capsule group and electropositive drug group.After taring medicine,observed LDL,AST and the changement histopathology of cardis tissue were examined. The data was done with by t-test. Results the mouse's level of LDH,AST in electropositive drug group is lower than in model group(p<0.001),and the degree of changement in histopatho1ogy is less compared with model groupmouse.Conclusion This experimlent shows that Yishenhuoxue capsules can treat viral myocarditis effectively.
Keywords:Yishenhuoxue capsules   mouse  LDH  AST  histopathology
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