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文拉法辛与舍曲林治疗抑郁症对照研究
引用本文:何蕊芳,李忠义,李刚,王秀梅.文拉法辛与舍曲林治疗抑郁症对照研究[J].临床精神医学杂志,2010,20(1):49-50.
作者姓名:何蕊芳  李忠义  李刚  王秀梅
作者单位:甘肃天水市精神病院,741000
摘    要:目的:比较文拉法辛与舍曲林治疗抑郁症的临床疗效和安全性。方法:将76例抑郁症患者随机分为文拉法辛组(38例)和舍曲林组(38例),疗程6周。采用汉密尔顿抑郁量表17项(HAMD)评定疗效,治疗中出现的症状量表(TESS)评定不良反应和安全性。结果:文拉法辛组治疗1周起效;疗程结束时,两组疗效和HAMD评分差异无显著性,不良反应少而轻。结论:文拉法辛与舍曲林治疗抑郁症疗效相似,文拉法辛起效较快。

关 键 词:抑郁症  文拉法辛  舍曲林

Comparative study between venlafaxine and sertraline in treatment of depression
HE Rui-fang,LI Zhong-yi,LI Gang,WANG Xiu-Mei.Comparative study between venlafaxine and sertraline in treatment of depression[J].Journal of Clinical Psychological Medicine,2010,20(1):49-50.
Authors:HE Rui-fang  LI Zhong-yi  LI Gang  WANG Xiu-Mei
Institution:HE Rui-fang,LI Zhong-yi,LI Gang,WANG Xiu-Mei.Tianshui Mental Hospital,Tianshui 741000,China
Abstract:Objective: To compare the clinical efficacy and safety of venlafaxine and sertraline in the treatment of depression. Method:Seven-six patients with depression were randomly divided into venlafaxine group or sertraline group and then received treatments for 6 weeks.The efficacy was assessed using Hamilton rating scale for depression(HAMD) and treatment emergent symptom scale(TESS). Results:The venlafaxine group showed treatment effect at week 1.There were no significant differences in the efficacy and HAMD s...
Keywords:depression  venlafaxine  sertraline  
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