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复方苏润江滴丸提取工艺研究
引用本文:刘桂花,薛桂蓬,邢建国,谢婷. 复方苏润江滴丸提取工艺研究[J]. 中国现代应用药学, 2013, 30(4): 399-403
作者姓名:刘桂花  薛桂蓬  邢建国  谢婷
作者单位:新疆维吾尔自治区药物研究所,新疆维吾尔自治区药物研究所,新疆维吾尔自治区药物研究所
基金项目:新疆维吾尔自治区重大科技专项(201130105-3)
摘    要:目的 优选复方苏润江滴丸提取工艺。方法 采用正交试验设计,分别以秋水仙碱含量、芦荟苷含量和浸膏得率为指标,优选秋水仙等3味药材的乙醇提取工艺;以总多糖含量和浸膏得率为指标,优选盒果藤根皮等4味药材的水提取工艺。结果 3味药材的最佳提取工艺为8倍量70%乙醇,提取2次,每次1.0h;4味药材的最佳提取工艺为10倍量水,提取3次,每次1.5h。结论 优选的提取工艺稳定、可行。

关 键 词:秋水仙碱  芦荟苷  总多糖  正交试验  提取工艺
收稿时间:2012-06-28
修稿时间:2012-10-13

Study on Extraction Process of Compound Surunjiang Dripping Pill
LIU Guihu,XUE Guipeng,XING Jianguo and XIE Ting. Study on Extraction Process of Compound Surunjiang Dripping Pill[J]. The Chinese Journal of Modern Applied Pharmacy, 2013, 30(4): 399-403
Authors:LIU Guihu  XUE Guipeng  XING Jianguo  XIE Ting
Affiliation:Xinjiang Institute of Meteria Medica,Xinjiang Institute of Meteria Medica,Xinjiang Institute of Meteria Medica
Abstract:OBJECTIVE To optimiza the extraction process of Compound Surunjiang Dripping Pill. METHODS Orthogonal experimental design was used for the optimization, the extract yield, the content of colchicine and aloin were taken as the indexes in extracting process of three herb medicines; the extract yield and the content of polysaccharide were taken as the indexes in extracting process of four herb medicines. RESULTS The optimum extraction progress was as follows: three herb medicines were extracted 2 times for 1 hour with 8 times amount of 70% alclhol; four herb medicines were extracted 3 times for 1.5 hour with 10 times amount of water. CONCLUSION The optimum extraction process was stable and feasible.
Keywords:colchicine   aloin   polysaccharide   orthogonal test   extraction technique
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