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Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock: a prospective randomized trial |
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| Authors: | Pekka Loisa Ilkka Parviainen Jyrki Tenhunen Seppo Hovilehto Esko Ruokonen |
| Affiliation: | 1.Department of Intensive Care, Päijät-Häme Central Hospital, Keskussairaalankatu 7, FI 15850 Lahti, Finland;2.Department of Intensive Care, Kuopio University Hospital, P.O. Box 1777, FI 70211 Kuopio, Finland;3.Department of Intensive Care, Tampere University Hospital, P.O. Box 2000, FI 33521 Tampere, Finland;4.Department of Intensive Care, South Carelian Central Hospital, Valto Käkelän katu 1, FI 53130 Lappeenranta, Finland |
| Abstract: | IntroductionLow-dose hydrocortisone treatment is widely accepted therapy for the treatment of vasopressor-dependent septic shock. The question of whether corticosteroids should be given to septic shock patients by continuous or by bolus infusion is still unanswered. Hydrocortisone induces hyperglycemia and it is possible that continuous hydrocortisone infusion would reduce the fluctuations in blood glucose levels and that tight blood glucose control could be better achieved with this approach. |
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