多巴胺联合硝普钠治疗慢性心力衰竭的疗效观察

目的观察多巴胺与硝普钠联合治疗慢性心力衰竭的疗效。方法回顾性分析2009年2月～2010年9月本院心内科收治住院的经确诊为慢性心力衰竭患者80例的临床资料,根据治疗方法的不同,将80例患者分成两组,对照组32例采用常规治疗心力衰竭,治疗组48例在此基础上加用微量泵输入多巴胺与硝普钠,对两组患者治疗的疗效进行对比。结果治疗后两组血压差异无统计学意义（P〉0.05）,心率和呼吸差异有统计学意义（P〈0.05）。治疗组中显效20例（41.7%）,有效26例（54.2%）,无效2例（4.1%）,总有效率为95.8%;对照组中显效0例,有效5例（15.6%）,无效27例（84.4%）,总有效率为15.6%;两组疗效比较差异有统计学意义（P〈0.05）。结论多巴胺与硝普钠治疗慢性心力衰竭能有效改善心功能,减少患者的住院时间。

Curative effects observation of dopamine combined with sodium nitroprusside in treatment of chronic heart failure

Objective To obverse the effect of dopamine combined with sodium nitroprusside in the treatment of chronic heart failure.Methods Clinical material of 80 cases of chronic heart failure patients from heart medicine department in our hospital from February 2009 to September 2010 were retrospectively analyzed and divided into two groups according to the different treatment methods.The control group of 32 cases was given the conventional treatment for heart failure,the treatment group of 48 cases was added dopamine combined with sodium nitroprusside by trace pump based on the control group,treatment effects of patients in two groups were compared.Results The blood pressure of two groups after treatment had no obvious difference(P > 0.05),the heart rate and breathing of two groups had significant difference(P < 0.05).In the treatment group,there were 20 cases(41.7%) of excellent,effective of 26 cases(54.2%),invalid of 2 cases(4.1%),the total effective rate was 95.8%;in the control group,there were 0 case of excellent,effective of 5 cases(15.6%),invalid of 27 cases(84.4%),the total effective rate was 15.6%;the curative effect of two groups had significant difference(P < 0.05).Conclusion Dopamine combined with sodium nitroprusside in treatment of chronic heart failure can effectively improve cardiac function,and reduce the time of hospitalization.