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帕罗西汀联合阿普唑仑治疗广泛性焦虑症的疗效观察
引用本文:甘剑平.帕罗西汀联合阿普唑仑治疗广泛性焦虑症的疗效观察[J].中国当代医药,2012,19(23):104-105.
作者姓名:甘剑平
作者单位:广东省佛山市南海区第九人民医院急诊科,广东佛山,528203
基金项目:广东省佛山市医学类科技攻关项目
摘    要:目的探讨帕罗西汀联合阿普唑仑治疗广泛性焦虑症患者的疗效,关注其对焦虑和抑郁评分的影响,以期为临床工作提供帮助。方法收集本院诊治的广泛性焦虑症的患者80例,随机分为观察组(40例)与对照组(40例),对照组单纯应用帕罗西汀治疗,观察组应用帕罗西汀联合阿普唑仑治疗,观察治疗对患者焦虑和抑郁评分的影响。结果观察组在治疗2、4、8周后对焦虑和抑郁的改善情况明显优于对照组,两组差异有统计学意义(P〈0.05)。结论帕罗西汀联合阿普唑仑治疗广泛性焦虑症患者的疗效明显,对焦虑和抑郁改善的效果理想,临床中可以积极应用。

关 键 词:广泛性焦虑症  帕罗西汀  阿普唑仑  焦虑  抑郁  临床观察

The clinical efficacy observation of paroxetine combined with alprazolam in treatment of generalized anxiety disorder
Authors:GAN Jianping
Institution:GAN Jianping The Ninth People’s Hospital of Nanhai District of Foshan City in Guangdong Province,Foshan 528203,China
Abstract:Objective To investigate the clinical efficacy of paroxetine combined with alprazolam in treatment of generalized anxiety disorder,to observe the anxiety and depression changes,for providing clinical help to clinical work.Methods Eighty patients with generalized anxiety disorder were divided into two groups.The control group(40 cases) were treated by paroxetine,the observation group(40 cases) were treated by paroxetine and alprazolam.The anxiety and depression scores were analyzed in the pre and post treatment.Results The changed scores of anxiety and depression were obviously higher in the observation group than in the control group after treatment of 2,4 and 8 weeks,there were significant differences(P < 0.05).Conclusion The treatment of paroxetine and alprazolam can improve the curative effect,decrease the scores of anxiety and depression,is worthy of being recommended in patients with generalized anxiety disorder.
Keywords:Generalized anxiety disorder  Paroxetine  Alprazolam  Anxiety  Depression  Clinical observation
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