梅毒血清和脑脊液2145例阳性检测结果分析

目的通过分析梅毒患者的血清和脑脊液检测结果,了解当前梅毒感染的现状,探讨进行临床检测的意义。方法采用非梅毒螺旋体抗原血清初筛试验(RPR,VDRL)和梅毒螺旋体抗原血清确证试验(TPPA,FTA-ABS)检测7049例性病门诊就诊者标本(血液6609例和脑脊液440例)中的螺旋体抗体,并分析检测结果。结果梅毒阳性者2145例,阳性率为30.43%,其中血标本阳性1989例,脑脊液标本阳性156例;一期梅毒为208例(9.70%),二期梅毒225例(10.49%),三期梅毒36例(1.68%),神经梅毒7.27%,胎传梅毒2.89%,隐性梅毒1458例(67.97%)。在2145例梅毒阳性患者的标本中,男性1021例,女性1124例,阳性率差异有显著性(P0.05)。梅毒以30～49岁发病率较高。结论正确的认识和解读梅毒血清学检测的临床意义,对于指导其在临床中的合理应用非常重要。

Analysis on Seral and Brain Spinal Fluid Positive Salmples From 2 145 Syphilis Cases

Objective To demonstrate current status of syphilis infection and significance of its clinical examinations.Methods Treponemal antibody in 7 049 samples (blood and cerebrospinal fluid) from venereal disease outpatients was detected,by non-treponemal antigen serum preliminary screening test (RPR,VDRL) and treponemal antigen serum verification test (TPPA,FTA-ABS).Results Two thousand one hurdred and forty-five cases were positive of syphilis with the incidence rate of 30.43%.Among those,primary syphilis was 9.70%,secondary syphilis was 10.49%,tertiary syphilis was 1.68%,neurosyphilis was 7.27%,congenital syphilis was 2.89% and latent syphilis was 67.97%.Total 2 145 positive cases consist of 1 021 male cases and 1 124 female cases.The incidence rates of males and females were significantltly different (P<0.05).The incidence rate was higher in 40～39 and 40～49 age groups than ofherse.Conlusions Clinical significance of syphilis serological detection should be correctly understood and interpretted,which is critical for its reasonble clinical applications.