| 六味地黄丸对甲亢型肾阴虚大鼠滋阴作用的研究 |
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| 引用本文： | 傅万山,丁伯平,杨解人. 六味地黄丸对甲亢型肾阴虚大鼠滋阴作用的研究[J]. 中国实验方剂学杂志, 2001, 7(5): 16-18 |
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| 作者姓名： | 傅万山 丁伯平 杨解人 |
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| 作者单位： | 安徽皖南医学院芜湖 241001 |
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| 摘 要： | 目的：观察六味地黄妨滋阴作用。方法：大鼠灌服3周甲状腺素造成甲亢型肾阴虚模型。结果：六味地黄丸能显著减慢阴虚大鼠心率，减少饮水量，增加尿量和体重，升高血糖、痛阈、甲状腺指数、血清IgG含量，降低血浆粘度，血清T3、T4、铜含量及铜／锌比值，呈明显剂量依赖关系。结论：六味地黄丸对甲亢型肾阴虚大鼠具有明显滋阴作用。
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| 关 键 词： | 六味地黄丸 肾阴虚模型 滋阴作用 中药 药理 |
| 文章编号： | 1005-9903(2001)05-0016-03 |
| 收稿时间： | 2001-02-09 |
| 修稿时间： | 2001-02-09 |
Study of Nourishing Yin Action of Six-Ingredient Rehmannia Pill in the Kindney Yin-deficiency Rats Induced by Hyperthyrea |
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| FU Wan-shan,DING Bo-ping,YANG Jie-ren. Study of Nourishing Yin Action of Six-Ingredient Rehmannia Pill in the Kindney Yin-deficiency Rats Induced by Hyperthyrea[J]. China Journal of Experimental Traditional Medical Formulae, 2001, 7(5): 16-18 |
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| Authors: | FU Wan-shan DING Bo-ping YANG Jie-ren |
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| Affiliation: | Dept of pharmacology,Wannan Medical College,Wu hu 241001 |
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| Abstract: | To observe the nourishing Yin action of Six-Ingredient Rehamnnia Pill (SIRP),Thyroxin (ig) was orally administrated to rats for 3 weeks in order to induce kidney yin-deficiency model of rats.Results showed SIRP markedly decreased the heart rate,plasma viscosity,serum T 3 and T 4,copper,the ratio of copper to zinc,and the intake of water,increased urine output,body weight,blood sugar,pain threshold,Index of thyroid and serum IgG contents.The dose-dependent relationship was significant.SIRP showed significant nourishing Yin action on kidney yin-deficiency rats induced by hyperthyrea. |
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| Keywords: | Six-Ingredient Rehmannia Pill model of kidney Yin-deficiency nourishing Yin action |
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