胰岛素泵短期治疗2型糖尿病的临床观察

目的：评价胰岛素泵在2型糖尿病病人中的短期治疗效果。方法：46例2型糖尿病病人分为两组进行强化胰岛素治疗，20例接受胰岛素泵持续皮下胰岛素输注(CSⅡ量组)，26例进行多次皮下胰岛素注射(MSⅡ组)，观察时间为10--30d。结果：两组达到稳定的目标血糖水平时，CSⅡ组所需的治疗时间、胰岛素量以及低血糖发生率明显比MSⅡ组减少(P＜0．05或P＜0．001)。结论：CSⅡ比MSⅡ更快、更有效地控制高血糖，降低低血糖的发生率。

A clinical study on treatment of type 2 diabetes by continuous subcutaneous insulin injection with insulin pump in a short period

Objective: To assess the short periodic efficacy of insulin pumping therapy in type 2 diabetes. Methods: 46 patients with type 2 diabetes were studied by two methods of intensive insulin therapy. In a period of 10 to 30 days, 20 patients were treated by continuous subcutaneous insulin injection (CSII) with insulin pump and 26 patients were received multiple subcutaneous insulin injection(MSII).Results: When 2 groups reached the stable target blood glucose value, the average duration of treatment, the daily insulin dose and the hypoglycemia incidence were markedly decreased in CSII group compared with MSII group. Conclusion: CSII method may control the hyperglycemia sooner and more effectively, and reduce the hypoglycemia risk compared with MSII.