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母牛分支杆菌菌苗治疗非典型分支杆菌肺病的临床观察
引用本文:崔冬梅,丁钰. 母牛分支杆菌菌苗治疗非典型分支杆菌肺病的临床观察[J]. 基层医学论坛, 2005, 9(4): 302-304
作者姓名:崔冬梅  丁钰
作者单位:枣庄市王开结核病防治院,山东,枣庄,277500
摘    要:目的评价母牛分支杆菌(微卡)菌苗对非典型分支杆菌(NTM)肺病的疗效。方法将31例经菌型鉴定为NTM肺病的患者随机分为A组(微卡组)和B组(对照组),B组采用4~6种敏感药物,A组在B组的基础上加用微卡,观察痰菌转阴及肺部病灶吸收情况。结果A组痰菌转阴率高于B组。肺部病灶吸收有显著性差异。结论微卡能加速痰菌转阴,提高免疫功能,是一种较好的免疫调节剂。

关 键 词:非典型分支杆菌 母牛分支杆菌 临床观察 肺病 菌苗治疗 病灶吸收情况 显著性差异 免疫调节剂 菌型鉴定 肺部病灶 免疫功能 微卡 B组 对照组 NTM 痰菌 转阴率
修稿时间:2004-12-01

A clinical study on Mycobacterium vaccae in the treatment of pulmonary disease caused by nontuberculous mycobacteria
Cui Dongmei,Ding Yu. A clinical study on Mycobacterium vaccae in the treatment of pulmonary disease caused by nontuberculous mycobacteria[J]. Public Medical Forum Magazine, 2005, 9(4): 302-304
Authors:Cui Dongmei  Ding Yu
Affiliation:Cui Dongmei,Ding Yu. Tuberculosis Hospital,Wang Kai Zao Zhuang,Shan Dong 277500
Abstract:Objective To study the effect of Mycobacterium vaccae(WeiKa)on nontuberculous mycobacteria(NTM)pulmonary disease. Methods 31 cases of NTM pulmonary disease diagnosed by identification of mycobacterium were classified randomly into group A(trial group)and group B (control group).Receiving 4~6 sensitive antituberculous drugs and 4~6 sensitive antituberculous plus vaccine of WeiKa regimens respectively. Resolution of pulmonary lesions and changes of negatove conversion of sputum were observed. Results Sputm negative conversion rates of group A was higher than group B.and significant difference was found in solution of pulmonary lesions. Conclusion WeiKa is a good immunotherapy preparation.It can promotes sputum negative conversion and activate immune function
Keywords:Mycobacterium caccae Nontuberculous mycobacteria Lung disease Immunology
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