老年血液病患者医院感染的临床分析

目的 探讨老年血液病患者医院感染的临床特点、危险因素及相关预防措施. 方法对2005年7月至2007年6月我院收治的581例老年血液病患者医院感染进行同顾性调查分析.结果 老年血液病患者发生医院感染177例,医院感染率为30.5%.感染例次率为43.7%.感染部位以下呼吸道最多,其次为肠道、上呼吸道.病原菌以革兰阴性杆菌为主(67.1%).危险因素为恶性疾病未缓解、并存多种慢性疾病、住院时间长、有院外感染、中性粒细胞减少、侵袭性操作、应用激素及应用广谱抗生素. 结论老年血液病患者易发生医院感染,针对危险因素采取有效预防措施,对降低老年血液病患者医院感染率有着重要意义.

Clinical analysis of nosocomial infection in senile patients with hematologic disorders

Objective To analyze the clinical characteristics, risk factors and prevention measures of nosocomial infection in senile patients with hematologic disorders. Methods The clinical data of 581 senile patients with hematologic disorders from July 2005 to June 2007 were retrospectively analyzed. Results The nosoeomial infection rate was 30.5%(177/581). The 581cases developed nosocomial infection for 254 times 43.7% (254/581)]. Lower respiratory tract infection was the most frequent infection site, followed by intestinal infection and upper respiratory infection. The species were predominated by Gram-negative bacillus (67.1%) . The risk factors of nosocomial infection were non-remission of malignant diseases,chronic underlying diseases, long time hospitaliation, community infection, granulocytopenia, invasive manipulation and application of adrenocortical hormone and antibiotic. Conclusions The nosoeomial infection rate is high in senile patients with hematologic disorders and it can be decreased by taking prevention measures according to the risk factors.