Three-dimensional echocardiographic virtual endoscopy for the diagnosis of congenital heart disease in children |
| |
Authors: | Haihong Xue Kun Sun Jianguo Yu Binjin Chen Guozhen Chen Wenjing Hong Liping Yao Lanping Wu |
| |
Institution: | (1) Department of Pediatric Cardiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China;(2) Department of Pediatric Cardiology, Shanghai Children’s Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China;(3) Department of Electronic Engineering, Fudan University, Shanghai, 200433, China;(4) Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China; |
| |
Abstract: | Virtual endoscopy (VE) is a new post-processing method that uses volumetric data sets to simulate the tracks of a “conventional”
flexible endoscope. However, almost all studies of this method have involved virtual visualizations of the cardiovascular
structures applied to computed tomography (CT) and magnetic resonance (MR) datasets. This paper introduces a novel visualization
method called the “three-dimensional echocardiographic intracardiac endoscopic simulation system (3DE IESS)”, which uses 3D
echocardiographic images in a virtual reality (VR) environment to diagnose congenital heart disease. The aim of this study
was to analyze the feasibility of VE in the evaluation of congenital heart disease in children and its accuracy compared with
2DE. Three experienced pediatric cardiologists blinded to the patients’ diagnoses separately reviewed 40 two-dimensional echocardiographic
(2DE) datasets and 40 corresponding VE datasets and judged whether abnormal intracardiac anatomy was present in terms of a
five-point scale (1 = definitely absent; 2 = probably absent; 3 = cannot be determined; 4 = probably present; and 5 = definitely
present). Compared with clinical diagnosis, the diagnostic accuracy of VE was 98.7% for ASD, 92.4% for VSD, 92.6% for TOF,
and 94% for DORV, respectively. Diagnostic accuracy of VE was significantly higher than that of 2DE for TOF and DORV except
for ASD and VSD. The receiver operating characteristic (ROC) curve for VE was closer to the optimal performance point than
was the ROC curve for 2DE. The area under the ROC curve was 0.96 for VE and 0.93 for 2DE. Kappa values (range, 0.73–0.79)
for VE and 2DE indicated substantial agreement. 3D echocardiographic VE can enhance our understanding of intracardiac structures
and facilitate the evaluation of congenital heart disease. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|