肝动脉化疗栓塞联合射频消融治疗中晚期肝癌的临床疗效分析

目的：评价联合应用肝动脉化疗栓塞和经皮射频消融治疗中晚期肝癌的临床应用价值。方法：经病理、AFP或影像学证实的符合标准的中晚期肝癌112例,按治疗方法随机分为单纯肝动脉化疗栓塞组（TACE）和TACE＋射频消融组（RFA）。TACE组54例,TACE＋RFA组58例。结果：TACE组治疗有效率为44%,联合治疗的有效率为68%,两组间差异有统计学意义（P〈0.01）;TACE组患者1年、2年和3年生存率分别为85%、64%和23%,中位生存期1.725年,联合介入治疗组患者1年、2年和3年生存率分别为93%、88%和79%,中位生存期为2.296年。联合介入治疗组的生存率及生存期显著高于TACE组（P〈0.05）。结论：联合应用肝动脉化疗栓塞和经皮射频消融治疗可显著提高中晚期肝癌患者的生存率,延长生存期。

Therapeutic effect of trans-arterial chemo-embolization in combination with radio-frequency ablation for the treatment of middle or advanced stage hepatocellular carcinoma

Objective:To evaluate the clinical value of trans-arterial chemoembolization(TACE)in combination with radio-frequency ablation(RFA)for the treatment of middle or advanced stage hepatocellular carcanoma(HCC).Methods:112 cases with pathology,AFP or imaging diagnosed middle or advanced stage HCC were divided into 2 groups according to their treatment.54 patients were enrolled into TACE group and 58 patients into the TACE+RFA group.Results:The effective rate was 44% for the TACE group and 68% for the TACE+RFA g...