布地奈德联合华法林钠治疗结肠炎75例疗效观察

目的 探讨布地奈德联合华法林钠治疗结肠炎的疗效.方法 将2009年1月至2011年6月在我院就诊的150例结肠炎患者随机分为治疗组和对照组各75例,治疗组联合使用布地奈德和华法林钠治疗,对照组仅用布地奈德,比较两组治疗前后的临床表现和疗效.结果 治疗组和对照组治疗前后,腹痛、腹泻、黏液血便、里急后重等临床表现的改善情况差异均有统计学意义(P＜0.05),且治疗组改善更明显；治疗组和对照组的治疗总有效率分别为96.0％和86.9％,差异有统计学意义(P＜0.05).结论 华法林钠与布地奈德的联用可改善结肠炎的疗效,可以进一步研究推广.

Clinical effect of Budesonide and Warfarin in the treatment of 75 cases of Colitis

Objective To observe the effect of Budesonide combined with Warfarin in the treatment of Colitis.Methods 150 patients of Colitis treated in our hospital from Jan.2009 to Jue.2011 were divided into two groups:the study group(treated by Budesonide combined with Warfarin) and the control group(treated by Budesonide),each with 75 cases.The clinical manifestation and curative effect were compared between the two groups.Results The manifestations,such as abdominal pain,diarrhea,mucous bloody stool,tenesmus were significantly alleviated after treatment,and the improvements in the study group were significantly more pronounced than those in the control group(P<0.05).The cure rate in the study group(96.0%) was significantly higher that in the control group(86.9%).Conclusion Budesonide combined with Warfarin can help improve the curative effect in the treatment of Colitis,which is worthy to be popularized.