男性泌尿生殖道支原体感染132例检测及药敏试验

目的为了解本地区泌尿生殖道支原体的感染状况,以及解脲支原体和人型支原体对不同药物的体外敏感性。方法对83例支原体标本做套式聚合酶链反应(nPCR)检测,其余进行培养和药物敏感性检测。结果132例样本中,解脲支原体(Uu)、人型支原体(Mh)、肺炎支原体(Mpn)、生殖支原体(Mg)4种支原体阳性率分别为66.5%、31.9%、27.7%、17.0%,发酵支原体(Mf)和穿通支原体(Mpe)均为2.7%,梨支原体(Mpi)未检出。Uu和Mh对抗生素高度敏感的依次为交沙霉素、美满霉素、强力霉素、阿奇霉素、克拉霉素。结论本地区男性性病病人支原体感染率较高。Uu和Mh感染对常见的红霉素、四环素等已产生一定的耐药性,及时进行药敏试验、选择高效药物,对降低Uu和Mh耐药株的产生、防止复发和提高治愈率将起到重要作用。

132 cases of mycoplasma infection and antibiotic susceptibility test pilot on Male urogenital tract

Objective To understand the region Urinary Mycoplasma genitalium infection, UU and mycoplasma to different drugs in vitro sensitivity. Methods 83 cases of Mycoplasma specimens got test of polymerase chain reaction (nPCR) detection, for the rest of the training and drug sensitivity. Results 132 samples, Ureaplasma urealyticum (Uu), 0.02 (11.90%), Mycoplasma pneumoniae (21.43%), Mycoplasma genitalium (Mg) four species of mycoplasma positive rate of 66.5%. 31.9%, 27.7%, 17.0%, M.fermentans (Mf) and the penetrating mycoplasma (Mpe) were 2.7%, pears mycoplasma (prostitutes) was not detected. Uu and Mh highly sensitive to antibiotics, in the following order Josamycin, minocycline, doxycycline, azithromycin, clarithromycin. Conclusions Mycoplasma infection is high in the region male STD patients. Uu and Mh infection on common erythromycin have generated some resistance. Timely test and choice of efficient drugs play an important role in reducing Uu Mh the selection of resistant strains, preventing recurrence and improving the cure rate.