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Promoted Transfection Efficiency of pDNA Polyplexes-Loaded Biodegradable Microparticles Containing Acid-Labile Segments and Galactose Grafts |
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| Authors: | Zhu Chen Xiaojun Cai Ye Yang Guannan Wu Yaowen Liu Fang Chen Xiaohong Li |
| Affiliation: | (1) Key Laboratory of Advanced Technologies of Materials Ministry of Education of China, School of Materials Science & Engineering, Southwest Jiaotong University, Chengdu, 610031, People’s Republic of China;(2) Research Institute of Tissue Engineering and Stem Cells, The Second Clinical Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of China; |
| Abstract: | PurposeTargeting to antigen-presenting cells and efficient intracellular delivery of pDNA are essential for development of microsphere formulations of DNA vaccine. |
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