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Circulating levels of a biomarker of collagen metabolism are associated with health-related quality of life in patients with chronic heart failure
Authors:Sofia V. Chatzikyriakou  Dimitrios N. Tziakas  Georgios K. Chalikias  Dimitrios Stakos  Dimitrios Papazoglou  Asimina Lantzouraki  Adina Thomaidi  Harisios Boudoulas  Stavros Konstantinides
Affiliation:(1) University Cardiology Department, Medical School, Democritus University of Thrace, Voulgaroktonou 23, 68100 Alexandroupolis, Greece;(2) University Internal Medicine Department, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;(3) Center for Clinical Research, Foundation of Biomedical Research, Academy of Athens, Athens, Greece;
Abstract:

Purpose  

Assessment of circulating levels of collagen-derived peptides has been proposed as a useful tool to monitor indirectly myocardial collagen metabolism in chronic heart failure (CHF) patients. The potential link between circulating concentrations of collagen metabolism biomarkers and health-related quality of life (HRQOL) has not been adequately evaluated. With the present study, we investigated the association between serum levels of collagen-derived peptides and HRQOL.
Keywords:
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