| 烧伤后脑功能异常患者神经元特异性烯醇化酶的变化 |
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| 引用本文： | 王广庆,王振国,肖仕初,夏照帆. 烧伤后脑功能异常患者神经元特异性烯醇化酶的变化[J]. 中华烧伤杂志, 2003, 19(6): 347-348 |
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| 作者姓名： | 王广庆 王振国 肖仕初 夏照帆 |
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| 作者单位： | 1. 200433,上海,第二军医大学长海医院全军烧伤中心
2. 辽宁省武警总医院烧伤科 |
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| 摘 要： | 目的 探讨烧伤患者伤后血浆中神经元特异性烯醇化酶 (NSE)含量与脑功能异常的关系。 方法 采用放射性免疫测定法 ,测定 11例出现精神、神经系统症状烧伤患者的NSE含量 ,分析全身炎症反应状态与NSE的相关性。 结果 烧伤后出现精神、神经系统症状的患者 ,血浆中NSE含量明显升高 (P <0 .0 1) ,并且NSE含量升高与全身炎症反应状态显著相关 (r =0 .899,P <0 .0 1)。 结论 测定NSE的变化 ,在一定程度上可以反映中枢神经系统受损害的程度。
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| 关 键 词： | 烧伤 脑功能 神经元特异性烯醇化酶 放射性免疫测定法 炎症反应 同工酶 |
| 修稿时间： | 2002-05-20 |
Postburn change in the plasma level of neuron specific enolase in burned patients with cerebral malfunction |
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| WANG Guang-qing,WANG Zhen-guo,XIAO Shi-chu,XIA Zhao-fan. Burns Center. Postburn change in the plasma level of neuron specific enolase in burned patients with cerebral malfunction[J]. Chinese journal of burns, 2003, 19(6): 347-348 |
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| Authors: | WANG Guang-qing WANG Zhen-guo XIAO Shi-chu XIA Zhao-fan. Burns Center |
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| Affiliation: | Burns Center. Changhai Hospital, The Second Military Medical University, Shanghai 200433, P.R. China. |
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| Abstract: | Objective To explore the relationship between the change in neuron specific enolase (NSE) and brain malfunction in burned patients. Methods The serum samples of 11 burned patients with brain dysfunction were collected for the development of the serum level of neuron specific enolase with radioimmunoassay, and the correlation between condition of systemic inflammation and the levels of neuron specific enolase was assessed. Results The level of NSE in burn patients with cerebral malfunction was obviously higher than that in control, and the level was correlated with the systemic inflammation. Conclusion The change in the level of serum NSE could reflect the damage degree of central nervous system to some extent. [ |
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| Keywords: | Phosphopyruvate hydratase Brain disease Burn |
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