| 活性炭在紫杉醇注射液中的应用研究 |
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| 引用本文： | 刘莉,罗佳波,邢学锋.活性炭在紫杉醇注射液中的应用研究[J].中国中药杂志,2006,31(9):735-736. |
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| 作者姓名： | 刘莉 罗佳波 邢学锋 |
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| 作者单位： | 南方医科大学,中医药学院,中药新药研究重点实验室,广东,广州,510515 |
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| 摘 要： | 目的:考察活性炭用量和温度对紫杉醇注射液质量的影响。方法:各测定方法照WS1-(X-026)-2001Z紫杉醇注射液项下规定,比较配制紫杉醇注射液时,不同用量活性炭及温度对紫杉醇注射液中紫杉醇含量,有关物质,澄明度及细菌内毒素的影响。结果:活性炭用量0.25%,温度35℃时,能保证紫杉醇注射液的质量。结论:配制紫杉醇注射液时,活性炭用量0.25%,温度35℃时为最佳。
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| 关 键 词： | 活性炭 紫杉醇 |
| 文章编号： | 1001-5302（2006）09-0735-02 |
| 收稿时间： | 2005-10-10 |
| 修稿时间： | 2005-10-10 |
Study on application of activated carbon in paclitaxel injection |
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| LIU Li;LUO Jia-bo;XING Xue-feng.Study on application of activated carbon in paclitaxel injection[J].China Journal of Chinese Materia Medica,2006,31(9):735-736. |
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| Authors: | LIU Li;LUO Jia-bo;XING Xue-feng |
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| Institution: | Southern Medical University, College of Traditional Chinese Medicine, Key Laboratory of Reasearch of Traditional Chinese Medicine and New Drug, Guangzhou 510515, China |
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| Abstract: | OBJECTIVE: To inspect the effect of activated carbon with different dosage and temperature on quality of paclitaxel injection. METHOD: Determinations in WS1-(X-026)-2001Z-paclitaxel injection were refered to compare the effect of different dosage and temperature for activated carbon on the taxol content, related material, clarity and bacterial endotoxin. RESULT: When used with 0.25% and 35 degrees C, activated carbon will ensure the quality of paclitaxel injection. CONCLUSION: 0.25% and 35 degrees C are the best condition when activated carbon is used in paclitaxel injection. |
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| Keywords: | activated carbon taxol |
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