奥拉西坦联合尼莫地平治疗血管性痴呆的疗效观察

目的观察奥拉西坦联合尼莫地平治疗血管性痴呆的疗效。方法将2011年5月至2013年3月我院收治的80例血管性痴呆患者随机分为观察组和对照组各40例，对照组患者采用一般常规治疗，观察组患者在一般常规治疗基础上加用奥拉西坦联合尼莫地平治疗，分析比较两组患者的疗效。结果观察组总有效率85％明显高于对照组的65％，观察组治疗后MMSE评分和ADL评分显著优于对照组（P〈0．05）。结论奥拉西坦联合尼莫地平治疗血管性痴呆疗效确切，具有协同加强作用，值得临床推广应用。

Observation on clinical effect of oxiracetam combined with nimodipine in the treatment of vascular dementia

Objective To observe the clinical effects of oxiracetam combined with nimodipine in the treatment of vascular dementia. Methods 80 patients with vascular dementia in our hospital from May 2011 to March 2013 were randomly divided into observation group and control group, 40 cases in each group. Observation group was given oxiracetam combined with nimodipine based on the general conventional method, and control group was given only general conventional method. Then the curative effects of two groups were analyzed and compared. Results After treatment, the clinical effect, MMSE grade, and ADL grade in the observation group were significantly better than those in the control group. Conclusion The curative effect of the oxiracetam combined with nimodipine in the treatment of vascular dementia is exact, which has collaborative strengthening effect. It is worthy to be popularized in clinic.