| 植物雌激素干预乳腺癌的研究进展 |
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| 引用本文： | 侯建峰,冯笑山.植物雌激素干预乳腺癌的研究进展[J].临床肿瘤学杂志,2010,15(1):82-85. |
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| 作者姓名： | 侯建峰 冯笑山 |
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| 作者单位： | 河南科技大学第一附属医院肿瘤科 河南科技大学肿瘤研究所 |
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| 基金项目： | 河南省医学科技攻关项目(200703082) |
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| 摘 要： | 以大豆异黄酮为代表的植物雌激素是一种广泛存在于植物中、与雌激素结构相似的生物活性物质。特别是大豆异黄酮在预防和治疗肿瘤、心血管疾病、骨质疏松、老年性痴呆和更年期疾病等方面的研究受到广泛重视，而其与乳腺癌发生、发展的关系更是成为研究的焦点。本文就大豆异黄酮的分类、代谢和抗乳腺癌作用机制以及与乳腺癌的流行病学、动物实验、人群干预等方面的研究进展情况作一综述。
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| 关 键 词： | 植物雌激素 大豆异黄酮 乳腺癌 预防 |
| 收稿时间： | 2009-07-23 |
| 修稿时间： | 2009-08-20 |
The advance of researches on the intervention of phytoestrogen in breast cancer |
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| HOU Jian-feng,FENG Xiao-shan.The advance of researches on the intervention of phytoestrogen in breast cancer[J].Chinese Clinical Oncology,2010,15(1):82-85. |
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| Authors: | HOU Jian-feng FENG Xiao-shan |
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| Institution: | HOU Jian-feng,FENG Xiao-shan.Department of Oncology,the First Affiliated Hospital of Henan University of Science , Technology,Henan University of Science , Technology Cancer Institute,Luoyang 471003,China |
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| Abstract: | Represented in soybean isoflavone,phytoestrogen is a bioactive substance widely consist in plants and structurally similar to estrogen.In particular,the researches of prevention and treatment of soy isoflavone on cancer,cardiovascular disease,osteoporosis,Alzheimer's disease,and menopause have been extensivelly attentioned.And its relationship with the occurrence and development of breast cancer has become the focus of the research.In this paper,the progress of soy isoflavones on the classification,metaboli... |
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| Keywords: | Phytoestrogen Soy isoflavone Breast cancer Prevention |
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