Determination of cocaine in human hair by gas chromatography/mass spectrometry |
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| Authors: | S. Balabanova J. Homoki |
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| Affiliation: | (1) Department of Forensic Medicine, University of Ulm, Prittwitzstraße 6, D-7900 Ulm, Federal Republic of Germany;(2) Department of Pediatrics, University of Ulm, Prittwitzstraße 6, D-7900 Ulm, Federal Republic of Germany |
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| Abstract: | Summary A qualitative method for the determination of cocaine alone without its metabolites in human hair by gas chromatography/mass spectrometry (GC/MS) was developed. The assay used helium as carrier gas, a 30-m bonded phase fused silica OV-1 capillary column, and solid injection at 290°C evaporator temperature.The cocaine concentrations in hair were determined also by radio-immunoassay (RIA). The values obtained are the sum of cocaine and its metabolites.Both GC/MS and RIA meet the requirements for the determination of drug abuse by two different methods in forensic science. |
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| Keywords: | Cocaine, gas chromatography/mass spectrometry Human hair, determination of cocaine |
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