下肢创伤后深静脉血栓形成的多元相关研究

目的 探讨影响下肢创伤后深静脉血栓形成(DVT)的相关因素及其多元关系.方法 对2006年8月至2008年3月2727例创伤患者进行回顾性分析,并于手术前行常规彩色多普勒超声检查双下肢DVT的发生.对17项临床因素与创伤后DvT形成的相关性进行了分析.结果 下肢创伤后DVT的患者有351例,DVT的发生率为12.9%.经Logistic多因素回归分析,与DVT相关的因素有4个,其中年龄增大和受伤至检查时间增长使创伤后发生DVT的风险分别增加1.484、1.816倍(P<0.05);女性和无合并伤使创伤后发生DVT的可能性分别减少到0.637、0.671倍(P<0.05).结论 年龄增大和受伤至检查时间增长是下肢创伤后发生DVT的危险因素,提示我们对高危因素患者最好行常规超声检查,以便及时治疗.

A multl-factorlal correlation analysis of deep vein thrombosis after trauma to lower extremities

Objective To investigate the multiple correlation factors of deep vein thrombosis after trauma to lower extremities. Methods A total of 2727 patients with traumas from pelvis to ankle were admitted from August 2006 to March 2008 and detected by Color Doppler ultrasound for DVT of bilateral lower extremities before operation. Emergency internal fixation or external fixation was not used for all patients before operation. Seventeen clinical factors were examined in order to analyze their influences upon DVT occurrence after trauma. Results DVT occurred in 351 patients after trauma. The incidence of DVT in all patients was 12.9%. The analysis of logistic regression demonstrated a definite correlation with the increment of age, the length of presentation time and the gender of female. No associated injury lowered the odds ratio of DVT down to 1.484, 1.816, 0.637 and 0.671 respectively. Other clinical factors had no statistically significant correlation with DVT. Conclusion Both the increment of age and the length of presentation time are risk factors for DVT after trauma to lower extremities. It is best to perform conventional ultrasound examinations in patients with these risk factors so as to timely treat a possible DVT.