血管内支架成形术治疗颅内动脉狭窄的临床疗效评价

目的　评价血管内支架成形术治疗颅内动脉狭窄的初步效果。方法　 39例颅内动脉狭窄患者 (19例后循环狭窄 ,2 0例为前循环狭窄 ) ,应用球囊膨胀型支架行腔内成形术治疗。结果　支架均一次成功植入 ,无手术相关并发症。术前术后平均血管狭窄程度分别为 73 5 %± 6 7%、11 2 %± 4 3%。临床随访 4～ 2 4个月 ,无脑缺血再发作或中风 ;脑血管造影随访 2 9例患者 ,均无血管再狭窄。结论　血管内支架成形治疗颅内动脉狭窄是安全、可行的 ,有助于降低中风的发生率。长期疗效需要进一步观察。

Endovascular stent-assisted angioplasty for atherosclerotic intracranial stenosis,a clinical analysis of 39 cases

OBJECTIVE: To assess the preliminary outcome of endovascular stent-assisted angioplasty for intracranial stenosis. METHODS: Thirty-nine patients with atherosclerotic intracranial stenosis (19 cases in posterior circulation and 20 in anterior circulation) were treated with endovascular angioplasty using balloon-expandable coronary stents. Follow-up was made for 4 - 24 months. The clinical manifestations were observed and CT, MR, or DSA were conducted before and after the operation. RESULTS: All of the stents were successfully implanted on the first procedure without procedural and periprocedural complications. The mean carotid artery stenosis rate was 73.5 +/- 6.7% before the procedure and 11.2 +/- 4.3% after the procedure. The patients were clinical asymptomatic and neurologically intact. Follow-up angiographies made in 29 patients revealed no restenosis. CONCLUSION: With effective short-term results and helpful in decreasing incidence of stroke, endovascular stenting is safe and feasible for treatment of intracranial stenosis.