六分钟行走试验：运动耐力评价的方法及临床意义

背景：6分钟行走试验是一项便于操作、易于耐受、能较好反映患者日常运动状况的运动耐力试验。近年来6分钟行走试验还用于评价心、肺移植后的功能状态。尤其对于肺移植后原发性移植物无功能患者的运动能力评价具有一定价值。目的：综述6分钟行走试验在运动耐力评价中的应用及研究进展。方法：以PubMmed和中国知网为检索工具,检索关于6分钟行走试验方法及其在胸肺疾病中应用的文章。检索时间范围：1963-01/2010-10,中文关键词为＂6分钟行走试验,慢性阻塞性肺疾病＂,英文关键词为＂6MWT,COPD＂。排除重复研究及Meta分析类文献。结果与结论：从PubMed和中国知网检索文献40余篇,选择其中23篇作为参考文献。其中论著20篇,指南2篇,述评1篇。结果提示6分钟行走试验对于评价慢性阻塞性肺疾病患者运动耐力和预测预后具有较大的应用价值,且简便易行,重复性好,能客观反映患者的病情状况。

Methods and clinical significance of six-minute walk test in evaluating exercise tolerance

BACKGROUND：6 minute walk test （6MWT） is a simple exercise tolerance test that can reflect daily exercise condition of patient. It has also been used to evaluate heart and lung functions following transplantation. In particular,it is valuable in evaluating exercise condition of patients with primary nonfunction following lung transplantation. OBJECTIVE：To review the application of 6MWT in evaluation exercise tolerance. METHODS：A computer-based online search of PubMed （http：//www.ncbi.nlm.nih.gov/pubmed/） and CNKI （http：//www.cnki.net/） was performed for articles published from January 1963 to October 2010 related to 6MWT methods and its application in chronic pulmonary obstructive disease （COPD） with key words ＂6MWT,COPD＂ in English and Chinese. Repetitive studies and Meta analysis were excluded. RESULTS AND CONCLUSION：Of 40 papers gotten from the database,23 were selected,including 20 original articles,2 guidelines,and 1 commentary. Results show that 6MWT is a useful method to evaluate exercise tolerance and predicate outcome of patients with COPD.