| 干扰素α-2b与拉米夫定治疗慢性乙型肝炎的成本-效果分析 |
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| 引用本文： | 王若伦,叶晓光. 干扰素α-2b与拉米夫定治疗慢性乙型肝炎的成本-效果分析[J]. 中国药房, 2002, 13(7): 405-406 |
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| 作者姓名： | 王若伦 叶晓光 |
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| 作者单位： | 广州医学院附属第二医院,广州市510260 |
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| 摘 要： | 目的 :评价应用干扰素α -2b与拉米夫定治疗慢性乙型肝炎的疗效、不良反应及成本 -效果。方法 :运用药物经济学成本 -效果分析方法 ,对干扰素α -2b与拉米夫定治疗慢性乙型肝炎的疗效及成本进行比较。结果 :干扰素α -2b与拉米夫定治疗慢性乙型肝炎总有效率基本相同 ,分别为58 00 %、62 00 % (P>0 05) ;成本 -效果比分别为762 49、111 85(P<0 01)。结论 :干扰素α -2b与拉米夫定均能有效治疗慢性乙型肝炎 ,但拉米夫定成本 -效果比优于干扰素α -2b。
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| 关 键 词： | 干扰素α-2b 拉米夫定 慢性乙型肝炎 成本-效果分析 |
| 文章编号： | 1001-0408(2002)07-0405-02 |
| 修稿时间： | 2001-12-24 |
A Comprison of Cost- effectiveness Between Interferon α - 2b and Lamivudine in Treating Chronic Hepa- titis B |
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| WANG Ruolun,YE Xiaoguang. A Comprison of Cost- effectiveness Between Interferon α - 2b and Lamivudine in Treating Chronic Hepa- titis B[J]. China Pharmacy, 2002, 13(7): 405-406 |
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| Authors: | WANG Ruolun YE Xiaoguang |
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| Abstract: | OBJECTIVE:To compare the therapeutic effects,adverse reactions and the costs between Interferon α-2b and Lamivudine in the treatment of chronic hepatitis B METHODS:Using pharmacoeconomic cost-effectiveness analysis,Lamivudine was compared with Interferon α-2b in the treatment of 100 patients with chronic hepatitis B(divided into two groups) RESULTS:After treatment,the effective rates of Interferon α-2b and Lamivudine were 58 00% and 62 00% respec_tively(P>0 05),the cost-effectiveness ratios were 762 49 and 111 85 respectively(P<0 01) CONCLUSION:Both of Inter_feron α-2b and Lamivudine can effectively treat chronic hepatitis B,the cost-effectiveness ratio of Lamivudine is superior to that of Interferon α-2b |
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| Keywords: | Interferon α-2b Lamivudine chronic hepatitis B cost-effectiveness analysis |
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